HEALTH & FOOD / DISTRIBUTED

BBMRI-ERIC

Biobanking and BioMolecular Resources Research Infrastructure
General Info
headquarters

BBMRI-ERIC

Graz, Austria

legal status
type

distributed

access

virtual, remote

description
The Biobanking and BioMolecular resources Research Infrastructure (BBMRI) is the European Research Infrastructure for Biobanking and Biomolecular Resources in health and life sciences. . Entered in the ESFRI Roadmap 2006, BBMRI became a European Research Infrastructure Consortium (ERIC) in December 2013. BBMRI brings together 25 members and observers, including an intergovernmental organisation: Members are Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Estonia, Finland, Germany, Greece, Hungary, Italy, Latvia, Lithuania, Malta, Netherlands, Norway, Poland, Slovenia, Sweden, Switzerland and observers are Denmark, IARC/WHO, Qatar, Spain, and finally Turkey. Each member and observer has one National Node, which brings together the national communities in each country. BBMRI-ERIC is thus being one of the largest ERICs membership-wise. The core mission of BBMRI-ERIC embedded in its statutes is facilitating access to biobanks and biomolecular resources in collaboration with its National Nodes, aiming to improve the accessibility and interoperability of existing comprehensive collections, either population based or clinical-oriented, of biological samples from different (sub-)populations of Europe. Via its databases, BBMRI-ERIC connects around 400 biobanks, and close over 2600 collections across 32 countries, with 9,000 users in 2023. This makes BBMRI-ERIC the biggest biobank directory in the world. Besides strong IT service, BBMRI also offers quality management services (including co-creating of relevant standards though participation in ISO since 2015), does research and provides services in the area of ethical, legal and societal issues, and ensures smooth cooperation with its scientific community via its biobanking development services. BBMRI-ERIC is continuously expanding its membership and building partnerships with countries and biobanks in Europe and beyond. In this respect in 2022 BBMRI-ERIC put in place a Policy on membership of associated and third countries. This paved the way for Qatar becoming an observer in BBMRI-ERIC in 2022, based on a long-standing collaboration with the Qatar Biobank. Via its Stakeholder Forum, BBMRI fosters relations with Patient Organisations in its member and observer countries, as well as European level-organisations. In 2024 the Patient and Citizens pillar of BBMRI-ERIC brings together 26 patient organisations from 13 countries and European level one. Relations with industry are in focus on specific topics, such as cooperation for organisation of the European Biobank Week, which brings together about 700 members of the biobanking community on a yearly basis. Moreover, BBMRI-ERIC engages in a co-creation with industry partners on topic of greening in biobanking. BBMRI plays a vital role in structuring the European Research Area, by coordinating or participating in over 25 EU projects. Its engagement in projects are aligned with the overall EU policy priorities research and evolve around the EU Mission on cancer (e.g. CanSERV-coordination, EOSC4Cancer and UNCAN.eu), Beating Cancer Plan, EOSC (e.g., Corbel, EOSC-Life, EOSC Future, BBMRI membership of EOSC-A), Pandemic Preparedness (e.g., ISIDORe, BY-COVID, BBMRI-Directory), Personalised Medicine and Rare Disease Partnership, and the European Health Data Space (e.g. EHDS2 Pilot). In addition, BBMRI-ERIC is also coordinating the ERIC Forum project.
TIMELINE & ESTIMATED COSTS
Total Investment Design Preparation Implementation Operation 2700000 M€/year Project Landmark 2006 2008 2010 2012 2014 2016 2018 2020 2022 2024 2026 2028 2030 2032 2034 2036 2038 RM06 RM08 RM10 RM16 RM18 RM21 LA24
Roadmap Entry
as project: 2006
as landmark: 2016
Total investment
Design Phase
Preparation Phase
2008-2011
Implementation Phase
2011-2013
Operation start
2014
2700000 M€/year
IMPACTS
The socio-economic benefits of BBMRI-ERIC can be summarized in three ways: Economic impact: BBMRI-ERIC's services contribute to Member States' economies through involvement in EC projects. Analysis shows that all BBMRI members and observers had a bigger overall return in grant funding, where national beneficiaries and BBMRI were involved, compared to the membership fee payments to BBMRI-ERIC receive greater grant funding than their membership fees. From 2019 to January 2024, the average number of new EC projects amounted to 5,5 with an average maximum grant amount for BBMRI-ERIC as a beneficiary of approx. 2.460.000 EUR. Since 2013, the total maximum grant volume of projects where BBMRI-ERIC participated amounts to over 500M EUR (total max. grant amount), of this BBMRI-ERIC gained over 18M EUR of external EU funding. Social impact of ELSI: BBMRI-ERIC's ELSI service has broad societal reach, with its expertise accessible through online resources and educational webinars. From 2017-2023 ELSI conducted over almost 450 Ethics Checks, Helpdesk requests, and consultations, and contributed to publications listed in PubMed. KPIs: Together with its Member States and National Nodes BBMRI-ERIC has put in place 14 KPIs, that are reported on a yearly basis since 2022, gathering statistics on the amount of users in the BBRMI Directory and BBMRI Negotiator, amount of (successful) requests handled within and outside of the BBMRI negotiator, participants in the Stakeholder Forum, successful grants, spend hours and number of attendees in ELSI services and dialogues, the extended BBMRI Quality (Q)-Labels on Institute and Collection level, number of Certified/Accredited BBMRI Biobanks, Laboratories/Institutes or Expert Centres and Publications involving BBMRI. In 2023, BBMRI has collected impact examples across its community that are a direct result of the national communities engaging within BBMRI-ERIC as part of the 10 year BBMRI-ERIC anniversary, the impact stories are available on our website and podcast.
SERVICES
BBMRI-ERIC provides four categories of scientific services that focus on facilitation of access to quality-defined biobanks and biomolecular resources in an ethical, GDPR-compliant, way. More information can be found in the ESFRI Strategy Report on Research Infrastructures 2023. Information Technology (IT) service portfolio includes: the BBMRI-ERIC Directory, Federated Platform (Locator and Finder) and specialised tools e.g., RD-Connect Registry & Biobank Finder for rare diseases; the BBMRI-ERIC Negotiator as the facilitation and matchmaking platform; the BBMRI-ERIC Authentication and Authorisation Infrastructure (AAI), and; BBMRI-ERIC is strengthening interoperability by leading Minimum Information about Biobank Data Sharing (MIABIS) grassroot standardisation and as originator of FAIR-Health principles extending FAIR principles with quality/reproducibility, privacy protection and incentive aspects. ELSI offers guidance on legal frameworks, like GDPR and the Oviedo Convention, and fosters knowledge exchange on citizen engagement, participant vulnerability, data protection, and incidental findings in human research via: the ELSI Knowledge Base; the ELSI Helpdesk; the Ethics Check, and; Training The Quality Management (QM) service aids biobanks and researchers in aligning with international standards and fosters communication with standardisation organizations with: Information and guidance on international standards; Training and implementation support for standards; Biobank assessment and recognition through awarding the Quality Label for compliant biobanks, and; Developing new biobank-relevant standards. The Biobanking Development (BBD) service assists the community by: Providing technical support to new members/observers in establishing their National Node and network and offering expertise and training; Enhancing sample and data accessibility through negotiation facilitation and collaboration with industry partners like EIT Health, and; Promoting sample/data utilization through advanced technologies and involving BBMRI-ERIC Expert Centres.
Interconnections
BBMRI-ERIC
S S H D I G I T E N E E N V P S E
COOPERATION WITH OTHER RIs
BBMRI-ERIC collaborates with various Research Infrastructures (RIs), as outlined in the ESFRI Strategy Report on Research Infrastructures 2023. Notably: In 2023-2024 BBMRI-ERIC chairs the Life Science Research Infrastructures (LS RI) Science Cluster, encompassing the collaboration of ANAEE, EATRIS, ECRIN, ELIXIR, EMBRC, EMPHASIS, ERINHA, EU-OPENSCREEN, Euro-BioImaging, IBISBA, INFRAFRONTIER, INSTRUCT, MIRRI, and BBMRI-ERIC. BBMRI-ERIC serves as mandated organization to the EOSC Association, representing the ERIC community in 2023-2024. BBMRI-ERIC coordinated the 1st and coordinates the 2nd ERIC Forum project, shaping the alliance between the 28 ERICs, aiming to further structure the cooperation between ERICs and providing the Secretariat to the Executive Board of ERIC Forum. BBMRI-ERIC signed a Statement on Strategic Collaboration with ELIXIR in 2023, emphasising joint interests in knowledge sharing, ethical, legal, and societal issues (ELSI), and research data management. BBMRI-ERIC collaborates with EuroBioImaging in strategic EU projects and is developing cooperation with infrastructures in the preparatory phase, like EIRENE, or other relevant entities, such as ECRAID, EVAg or ESBB. BBMRI-ERIC participates in the European Alliance for Medical Research Infrastructures (EU-AMRI) with EATRIS and ECRIN to accelerate national synergies in shared member states (Czech Republic, Italy, Norway, Spain) and collaborating on strategic EU projects like canSERV, ISIDORe, and EOSC Life.